Atipam (atipamezole hydrochloride) is a synthetic  2-adrenergic antagonist which reverses the effects of dexmedetomidine hydrochloride and medetomidine hydrochloride in dogs. Atipam is indicated for the reversal of the clinical effects of the sedative and analgesic agents, dexmedetomidine hydrochloride and medetomidine hydrochloride, in dogs.